We offer Stem cell therapy, Platelet Rich Plasma (now known as E-PET) and IRAP (Interleukin1 receptor antagonist protein.) These biological products are regenerative medicines used as appropriate in the treatment of tendon, ligament and joint disease.
Stem cell therapy
Stem cell therapy uses cutting edge technology, founded on the pioneering work of Professor Roger Smith and his colleagues at the Royal Veterinary College. It is primarily used in tendon and ligament injuries and results in a better functional repair as well as reducing re-injury rate. Research has shown that it is the best way to treat injuries of the superficial digital flexor tendon.
The procedure involves bone marrow being aspirated from the sternum of the injured horse, and then in the laboratory, identification and expansion of mesenchymal stem cells. 10 million of these stem cells are then injected into the core lesion of the injured tendon or ligament, using ultrasound guidance.
For more information on the therapy please contact us.
Platelet Rich Plasma/E-PET
E-PET (Equine Platelet Enhancement Therapy) formerally known as Platelet-rich plasma or PRP, is obtained after blood taken from the horse is put through a special centrifugation process. This is a quick process, and the product of centrifugation can be injected into the damaged tendon or ligament on the same day. The product has a high concentration of platelets which are activated by contact with damaged tissue, and act by releasing growth factors to stimulate the healing process and decrease inflammation. It is most commonly used in the treatment of suspensory ligament lesions. It is also used to enhance wound healing, especially in problematic lower limb injuries.
We are now on the list of approved practices for Stem cell and E-PET therapy, and have attended training courses to ensure competency.
IRAP – Interleukin-1 receptor antagonist protein
This is a relatively new product developed in the human field for the treatment of joint disease.
IRAP therapy is recommended for horses suffering from mild to moderate osteoarthritis, capsulitis/synovitis, and following arthroscopic surgery. IRAP works by blocking interleukin-1, which is the major cytokine (chemical messenger) involved in the destruction of articular cartilage.
Levels of IRAP and other anti-inflammatory proteins in the blood can be increased by harvesting the horses own blood in specially prepared syringes containing coated glass beads, culturing and growing the protective factors.
Following 24-hours incubation the blood is centrifuged and the IRAP rich protein harvested. The serum is filtered and then frozen in single dose aliquots which are stored for injecting into the injured joint at a later date.